CH5447240 |CAS 1253919-92-45|DC Chemicals

Cas No.:	1253919-92-4
Chemical Name:	1-(3,5-Dimethyl-4-(2-((2-((1r,4r)-4-methylcyclohexyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-1-methylurea
Synonyms:	CH5447240;1-(3,5-dimethyl-4-(2-((2-((1r,4r)-4-methylcyclohexyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-1-methylurea;TQR0476;BDBM50457781;1-[3,5-dimethyl-4-[2-[[2-(4-methylcyclohexyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-1-methylurea
SMILES:	S(CCC1C(C)=CC(=CC=1C)N(C(N)=O)C)(N1CCC2(C(NC(C3CCC(C)CC3)=N2)=O)CC1)(=O)=O
Formula:	C₂₆H₃₉N₅O₄S
M.Wt:	517.683964967728
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

CH5447240 is a novel potent, selective, orally active hPTHR1 agonist with EC20 of 3.0 nM and EC50 of 12 nM; shows excellent physicochemical properties, such as high solubility in fasted state simulated intestinal fluid and good metabolic stability in human liver microsomes; demonstrates a significantly elevated serum calcium level in hypocalcemic model rats.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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