Cas No.: | 169675-08-5 |
Chemical Name: | (2S)-1-(6-Chloro-5-fluoroindol-1-yl)propan-2-amine |
Synonyms: | (2S)-1-(6-chloro-5-fluoroindol-1-yl)propan-2-amine;(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine;(S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;(S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine;GTPL166;BDBM50144841;BDBM50428891;ORG 35030;Ro600175;Q27088596;(2S)-1-(6-chloro-5-fluoroindol-1-yl)-propan-2-amine;(1S)-2-(6-chloro-5-fluoroindol-1-yl)-1-methylethylamine;(2S)-1-(6-chloro-5-fluoro-1H |
SMILES: | ClC1=C(C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])[C@]([H])(C([H])([H])[H])N([H])[H])F |
Formula: | C11H12ClFN2 |
M.Wt: | 226.6778 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo. |