SUVN-G3031|SUVN-G 3031

Cas No.:	1394808-82-2
Chemical Name:	Suvn-G3031
Synonyms:	65V47O9NOP;N-(4-((1-cyclobutylpiperidin-4-yl)oxy)phenyl)-2-morpholinoacetamide;Samelisant;GTPL10232;TQ0150;DB14835;N-[4-(1-Cyclobutyl piperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide;N-[4-(1-cyclobutyl-piperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide;N-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-2-morpholin-4-ylacetamide;Suvn-G3031
SMILES:	O(C1C=CC(=CC=1)NC(CN1CCOCC1)=O)C1CCN(CC1)C1CCC1
Formula:	C₂₁H₃₁N₃O₃
M.Wt:	373.489145517349
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R); exhibited an IC50 of 20 nM with progressive inhibition of (R)-α-methylhistamine (0.03 µM) induced agonist activity in [35S]-GTPγS binding assay using CHO-K1 cells expressing human H3R membranes; reverses (R)-α-methylhistamine induced dipsogenia in vivo.Parkinson DiseasePhase 1 Clinical

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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