NAPQI| CAS 50700-49-7|DC Chemicals

Cas No.:	50700-49-7
Chemical Name:	N-ACETYL-4-BENZOQUINONE IMINE
Synonyms:	N-ACETYL-4-BENZOQUINONE IMINE;N-(4-Oxo-1-cyclohexa-2,5-dienylidene)acetamide,N-Acetyl-p-benzo-quinoneimine,NAPQI;N-(4-oxocyclohexa-2,5-dien-1-ylidene)acetamide;N-(4-Oxo-1-cyclohexa-2,5-dienylidene)acetamide;NAPQI;N-Acetyl-1,4-benzoquinonimine;N-Acetyl-p-benzoquinone imine;N-Acetyl-p-benzoquinonimine;2,5-Cyclohexadien-1-one,4-(acetylimino)-
SMILES:	C(/N=C1\C=CC(=O)C=C\1)(=O)C
Formula:	C₈H₇NO₂
M.Wt:	149.146682024002
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A toxic byproduct, iminoquinone metabolite of acetaminophen that covalently binds to the active site of MIF; inhibits both the isomerase and the biological activities of MIF with IC50 of 40 uM; significantly inhibits the ability of MIF to override the immunosuppressive effect of dexamethasone on endotoxin- (LPS) stimulated TNFα production by monocytes.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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