3-Bromopyruvic acid

  Cat. No.:  DC22490   Featured
Chemical Structure
1113-59-3
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More than 5000 active chemicals with high quality for research!
Field of application
A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress.
Cas No.: 1113-59-3
Chemical Name: 3-Bromopyruvic acid
Synonyms: 3-Bromopyruvic acid;3-BROMO-2-OXOPROPANOIC ACID;3-BROMO-2-OXOPROPIONIC ACID;BROMOPYRUVIC ACID;3-bromo-2-oxo-propanoicaci;3-bromopyruvate;beta-bromopyruvicacid;bromopyruvate;bromo-pyruvicaci;3-BROMOPYRUVIC ACID CRYSTALLINE;Bromopyruvicacidhydrate;3-BROMO-2-OXOPROPANOICACID(3-BROMOPYRUVICACID);2-Oxo-3-bromopropanoic acid;2-Oxo-3-bromopropionic acid;3-BROMO-2-OXO-PROPIONIC ACID;3-BromopYHuvic acid;3-BROMOPYRUVIC ACID HYDRATE;3-BROMOPYRUVICACID(3-BROMOPYRUVATE);Hexokinase II Inhibitor II, 3-BP;PROPANOIC ACID,3-BROMO-2-OXO-;3-Bromo-2-oxopropionic Acid;NS00023565;NS00023565;EN300-67360;EN300-67360;CHEBI:95046;CHEBI:95046;Bromopyruvic acid; 3-bromo-2-oxopropanoic acid;Bromopyruvic acid; 3-bromo-2-oxopropanoic acid;Bromopyruvic acid, >=97.0% (T);Bromopyruvic acid, >=97.0% (T);3-bromo-2-oxopropanoic acid;3-Bromopyruvic acid;3-bromo-2-oxopropanoic acid;3-Bromopyruvic acid;bromopyruvic acid;bromopyruvic acid;3-BP;3-BP;.beta.-Bromopyruvic acid;NSC-62343;.beta.-Bromopyruvic acid;NSC-62343;EINECS 214-206-5;NSC 11731;EINECS 214-206-5;NSC782120;NSC 11731;FT-0623262;NSC782120;BRD-K92980438-001-01-7;FT-0623262;BRD-K92980438-001-01-7;Z1079181768;Z1079181768;Bromopyruvicacid;Bromopyruvicacid;Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3;Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3;3-Bromo-2-oxopropionic acid;3-Bromo-2-oxopropionic acid;NSC-11731;NSC-11731;Propanoic acid, 3-bromo-2-oxo-;3-bromo-2-oxo-propionic acid;Propanoic acid, 3-bromo-2-oxo-;J-650255;3-bromo-2-oxo-propionic acid;J-650255;1113-59-3;1113-59-3;BPV;BPV;CS-5517;NSC11731;CS-5517;Q3608257;NSC11731;NSC62343;Q3608257;3-BrPA;NSC62343;MFCD00002587;3-BrPA;Pyruvic acid, bromo-;HY-19992;MFCD00002587;3-Bromopyruvic acid hydrate,98;Pyruvic acid, bromo-;HY-19992;B1153;SCHEMBL8126;3-Bromopyruvic acid hydrate,98;bromo-2-oxopropanoic acid;B1153;beta-Bromopyruvic acid;SCHEMBL8126;s5426;bromo-2-oxopropanoic acid;AM84337;beta-Bromopyruvic acid;AS-16146;s5426;AKOS015892643;AM84337;63JMV04GRK;AS-16146;NSC 62343;AKOS015892643;63JMV04GRK;3-bromopyruvic acid;HMS3866H13;NSC 62343;CCG-266336;3-bromopyruvic acid;Hexokinase II Inhibitor II;3-BP;HMS3866H13;J-511892;CCG-266336;UNII-63JMV04GRK;Hexokinase II Inhibitor II;3-BP;BRN 1746786;J-511892;3-Bromo-2-oxopropanoic acid #;UNII-63JMV04GRK;CHEBI:131461;BRN 1746786;3-bromo-2-oxopropanoic acid;3-Bromo-2-oxopropanoic acid #;3-bromo-2-keto-propionic acid;CHEBI:131461;NSC-782120;3-bromo-2-oxopropanoic acid;HMS3741K19;3-bromo-2-keto-propionic acid;3-bromopyruvicacid;NSC-782120;DTXSID7040940;HMS3741K19;CHEMBL177837;3-bromopyruvicacid;NCIOpen2_000241;DTXSID7040940;CHEMBL177837;NCIOpen2_000241
SMILES: O=C(O)C(CBr)=O
Formula: C3H3BrO3
M.Wt: 166.96
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress; potentiates acetate-induced apoptosis and anti-proliferative effect in CRC cells; abrogates MUC1-mediated radiation resistance both in vitro and in vivo pancreatic cancer models, by reducing glucose flux into nucleotide biosynthetic pathways and enhancing DNA damage.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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