Cas No.: | 380607-77-2 |
Chemical Name: | CMPDA |
Synonyms: | CMPDA;[(methylethyl)sulfonyl]{2-[4-(2-{[(methylethyl)sulfonyl]amino}ethyl)phenyl]ethyl}amine |
SMILES: | O=S(NCCC1=CC=C(CCNS(=O)(C(C)C)=O)C=C1)(C(C)C)=O |
Formula: | C16H28N2O4S2 |
M.Wt: | 376.53452205658 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays; binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. |