Spliceostatin A| CAS 391611-36-2|DC Chemicals

Cas No.:	391611-36-2
Chemical Name:	SPLICEOSTATIN A
Synonyms:	SPLICEOSTATIN A
SMILES:	C/C(/C=C/[C@@H]1[C@@H](O)[C@]2(CO2)C[C@@](OC)(O1)C)=C\C[C@H]3[C@H](C[C@@H](NC(/C=C\[C@@H](OC(C)=O)C)=O)[C@H](O3)C)C
Formula:	C₂₈H₄₃NO₈
M.Wt:	521.643
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Spliceostatin A is a methylated derivative of FR-901464 that inhibits pre-mRNA splicing; inhibits in vitro splicing and promote pre-mRNA accumulation by binding to SF3b, a subcomplex of the U2 small nuclear ribonucleoprotein in the spliceosome; inhibits spliceosome assembly subsequent to prespliceosome formation.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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