Polyoxyethylene 40 stearate

  Cat. No.:  DC23907   Featured
Chemical Structure
9004-99-3
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
A non-ionic emulsifying agent that can modulate multidrug resistance and enhances antitumor activity of vinblastine sulfate by modulating substrate-stimulated P-gp ATPase activity.
Cas No.: 9004-99-3
Chemical Name: Polyoxyethylene stearate
Synonyms: polyoxyethylene 8 stearate;Polyethylene glycol monostearate;MYRJ(TM) 53;MYRJ(TM) 59;MYRJ 58;MYRJ 59;MYRJ(R) 53;MYRJ(TM) 45;MYRJ 45;PEG 200 STEARATE;Polyoxyethylene stearate;PEG1000monostearate;PEG1540monostearate;PEG300monostearate;PEG4000monostearate;PEG400monostearate;PEG600monostearate;POES;Poly(oxy-1,2-ethanediyl), .α.-hydro-.ω.-hydroxy-, octadecanoate;Polyethylene Glycol Monostearate (10E.O.);Polyethylene Glycol Monostearate (25E.O.);Polyethylene Glycol Monostearate (55E.O.);POLYETHYLENE GLYCOL MONOSTEARATE N-4 (PALMITATE AND STEARATE MIXTURE);Polyethylene Glycol Monostearate(45E.O.);n≈10;n≈100;n≈25;PEG-100 stearate;PEG-32 stearate;PEG-6 stearate;PEG-8 stearate;PEG-75 stearate;Myrj 52;PEG monostearate;ENaC alpha Antibody;2-Hydroxyethyl stearate;Glycol stearate;2-Hydroxyethyl octadecanoate;Ethylene glycol monostearate;Cremophor A;Cerasynt M;Clearate G;Cerasynt MN;Cithrol PS;Polyoxyl 40 stearate;Polystate;Lactine;Myrj;Cithrol 10MS;Cerasynt 660;Polystate B;Prodhybase P;Akyporox S 100;PEG stearate;Soromin-SG;Lamacit CA;Emerest 2640;Stearoks 6;Stearoxa-6;Stearox 6;Nikkol MYS;Pegosperse S 9;Glycol monostearate;Emanon 3113;Stenol 8;Emcol H 35-A;Arosurf 1855E40;Polyoxyl(40)Stearate
SMILES: O(C([H])([H])C([H])([H])O[H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O
Formula: C20H40O3
M.Wt: 328.5298
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A non-ionic emulsifying agent that can modulate multidrug resistance and enhances antitumor activity of vinblastine sulfate by modulating substrate-stimulated P-gp ATPase activity; inhibits P-gp mediated efflux in a concentration-dependent manner in Caco-2 cells, also shows potential inhibitory activitites agasint CYP2C9 and CYP2C19.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC74557 PREX-in1 PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain.
DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74540 MTX-3937 MTX-3937 is a small-molecule inhibitor targeting Siglec-9 (Sialic acid-binding immunoglobulin-type lectin-9), a member of the Siglec family of immunomodulatory receptors. Siglec-9 is primarily expressed on immune cells, such as myeloid cells and natural killer (NK) cells, and plays a role in regulating immune responses by transmitting inhibitory signals through its intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74225 YB-537 YB-537 (YB537) is a potent, highly specific quinone reductase 2 (QR2) inhibitor with IC50 of 3 nM, shows no activity against QR1 (IC50>10 uM).
DC74223 X-Neu5Ac X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase.
DC74218 UT-59 UT-59 is a specific inhibitor of cholesterol-sensing membrane protein Scap, binds to Scap's cholesterol-binding site, blocks SREBP activation and inhibits lipid synthesis.
DC74205 Tryptolinamide Tryptolinamide (TLAM) is a small-molecule compound that activates mitochondrial respiration in cybrids generated from patient-derived mitochondria and fibroblasts from patient-derived iPSCs, inhibits phosphofructokinase-1 (PFK1) with an ATP-uncompetitive
X