Atosiban GMP grade| CAS 90779-69-4

Cas No.:	90779-69-4
Chemical Name:	Atosiban
Synonyms:	Atosiban;1-deamino-2d-tyr-(oet)-4-thr-8-orn-oxytocin;oxytocin,1-(3-mercaptopropanoicacid)-2-(o-ethyl-d-tyrosine)-4-l-threonine-8-l;rwj22164;ATOSIBAN ACETATE;1-(3-Mercaptopropionic acid)-2-(3-(p-ethoxyphenyl)-D-alanine)-4-L-thre onine-8-L-ornithineoxytocin;[Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2;(2S)-N-[(1S)-4-Amino-1-(carbamoylmethylcarbamoyl)butyl]-1-[(4S,7S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;1-(3-Mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithineoxytocin;(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin;1-Deamino-2-D-Tyr-(O-ethyl)-4-Thr-8-ornoxytocin;RW22164;Tractocile;(2S)-N-[(1S)-4-Amino-1-(carbamoylmethylcarbamoyl)butyl]-1-[(4S;Antocin;Rwj 22164;dTVT;081D12SI0Z;Atosibanum [INN-Latin];deTVT;Atosibanum;ORF 22164;Antocin II;Atosiban [USAN:INN:BAN];1-(3-Mercaptopropionic acid)-2-(3-(p-ethoxyphenyl)-D-alanine)-4-L-threonine-8-L-ornithineoxytocin;C43H67N11O12S2;1-(3-Mercaptopropanoic acid)-2-(O-ethy;1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane, cyclic peptide deriv. (ZCI);Oxytocin, 1-(3-mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithine- (ZCI);Antocile;CAP 449;CAP 476;CAP 581;F 314;RW 22164;DTXSID90861122;CAS_90779-69-4;(2S)-N-[5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,16R)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-ethoxyphenyl)methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;AKOS015895131;MFCD00672436;NCGC00387803-01;BCP02053;1-[7-(2-Amino-2-oxoethyl)-13-(butan-2-yl)-16-[(4-ethoxyphenyl)methyl]-10-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]prolylornithylglycinamide;SY301205;BDBM86209;90779-69-4;CAP-476;CAP-476;CAP-476;CAP-476;CAP-476;ATOSIBAN (MART.);ATOSIBAN (MART.);ATOSIBAN (MART.);ATOSIBAN (MART.);ATOSIBAN (MART.);d(D-Tyr(Et)2,Thr4,Orn8)vasotocin;d(D-Tyr(Et)2,Thr4,Orn8)vasotocin;d(D-Tyr(Et)2,Thr4,Orn8)vasotocin;d(D-Tyr(Et)2,Thr4,Orn8)vasotocin;d(D-Tyr(Et)2,Thr4,Orn8)vasotocin;RW22164;RWJ22164;RW22164;RWJ22164;RW22164;RWJ22164;RW22164;RWJ22164;RW22164;RWJ22164;C77085;C77085;C77085;C77085;C77085;CAS-90779-69-4;CAS-90779-69-4;CAS-90779-69-4;CAS-90779-69-4;CAS-90779-69-4;Atosibanum (INN-Latin);Atosibanum (INN-Latin);Atosibanum (INN-Latin);Atosibanum (INN-Latin);Atosibanum (INN-Latin);(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin acetate salt;(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin acetate salt;(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin acetate salt;(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin acetate salt;(Deamino-Cys1,D-Tyr(Et)2,Thr4,Orn8)-Oxytocin acetate salt;DTXSID8048991;DTXSID8048991;DTXSID8048991;DTXSID8048991;DTXSID8048991;GTPL2213;...
SMILES:	C([C@@H]1CSSCCC(=O)N[C@H](CC2C=CC(OCC)=CC=2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CC(=O)N)C(=O)N1)(N1CCC[C@H]1C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N)=O
Formula:	C₄₃H₆₇N₁₁O₁₂S₂
M.Wt:	994.188587427139
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Atosiban(RW22164; Tractocile) is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra). Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane.As a result, there is reduced release of intracellular, stored calcium from the sarcoplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition, atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua.[1][2] In human pre-term labour, atosiban, at the recommended dosage, antagonises uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid, uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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