NM107

  Cat. No.:  DC23940   Featured
Chemical Structure
20724-73-6
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More than 5000 active chemicals with high quality for research!
Field of application
NM-107, also known as 2'-C-Methylcytidine; 2'-C-MeC; 2-CMC; mCyd ; 2'CMeC; 2CMC, is a a potent and selective anti-viral drug. NM-107 showed activity to inhibit the replication of foot-and-mouth disease virus. NM-107 exerts potent anti-DENV activity in DENV subgenomic RNA replicon and infectious systems, with an IC50 value of 11.2±0.3μM. NM-107 may be a promising compound for the development of direct-acting antivirals against DENV infection.
Cas No.: 20724-73-6
Chemical Name: NM107
Synonyms: 2'-C-Methylcytidine;NM107;2’-C-Methyl Cytidine;2''-C-Methylcytidine;4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one;1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one;2'-METHYLCYTIDINE;Cytidine,2'-C-methyl;NM-107;UNII-27FS20C1D8;valopicitabine;2′-C-Methyl Cytidine;Cytidine, 2'-C-methyl-;NM 107;27FS20C1D8;2 inverted exclamation mark -C-Methylcytidine;4-amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one;2'-C-Methyl Cytidine;2'-C-methyl-cytidine;(+)-2'-C-Methylcytidine;2'-C-Mecytosine;Cm-c-methylcytidine;4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-yl]pyrimidin-2-one;EOS91;2'C-Me-C;F12743;2(1H)-pyrimidinone, 4-amino-1-(2-C-methyl-.beta.-D-ribofuranosyl)-;PPUDLEUZKVJXSZ-VPCXQMTMSA-N;BRD-K79424231-001-01-2;AS-57663;DTXSID40174799;AM84720;HY-10468;CS-4944;2'-C-Methylcytidine, >=95% (HPLC), powder;Q27254201;2'-C-methylcytidine;MFCD02682947;2'C-methylcytidine;SCHEMBL141004;2''''C-Me-C;NCGC00484060-01;2''''-C-Methylcytidine;BDBM50530022;DB13921;20724-73-6;AKOS016004503;NS00069295;4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2-dihydropyrimidin-2-one;BP-58657;CHEMBL438605;2'-C-Mecytosin;2''''-C-Mecytosine
SMILES: O1[C@]([H])(C([H])([H])O[H])[C@]([H])([C@](C([H])([H])[H])([C@]1([H])N1C(N=C(C([H])=C1[H])N([H])[H])=O)O[H])O[H]
Formula: C10H15N3O5
M.Wt: 257.2432
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells; The active component of NM283.HCV InfectionPhase 2 Discontinued
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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