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Cevimeline hydrochloride

  Cat. No.:  DC23951   Featured
Chemical Structure
107220-28-0
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More than 5000 active chemicals with high quality for research!
Field of application
Cevimeline HCl is a cholinergic agonist that binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands, and increase tone of the smooth muscle in the GI and urinary tracts.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 107220-28-0
Chemical Name: Cevimeline hydrochloride
Synonyms: Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane],2'-methyl-, hydrochloride (1:1), (2'R,3R)-rel-;Cevimeline Hydrochloride Salt;2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane],hydrochloride;CEVIMELINE;Cevimeline hydrochloride;Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane],2'-methyl-, hydrochloride (1:1), (2'R,3...;AF-102B hydrochloride;SNI-2011 hydrochloride;Saligren;cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride;AF 102B;Evoxac;FKS 508;SND 5008;SNI 2011;SNK 508;(2'R,3R)-rel-2'-Methyl- spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane] hydrochloride;CeviMelin;CeviMeline hydrochloride Saligren;(2R,3'R)-2-methyl-1'-azaspiro[[1,3]oxathiolane-5,3'-bicyclo[2.2.2]octane] hydrochloride;(2R,3'R)-2-methyl-1'-azaspiro[[1,3]oxathiolane-5,3'-bicyclo[2.2.2]octane] hydrochloride;SCHEMBL838481;SCHEMBL838481;DTXSID10891421;DTXSID10891421;EN300-6497318;EN300-6497318;MS-23364;MS-23364;Cevimeline,hydrochloride salt;Cevimeline,hydrochloride salt;CS-4000;(2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride;CS-4000;(2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrochloride;124620-89-9;124620-89-9;HY-70020B;HY-70020B;(2R,5'R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] hydrochloride;(2R,5'R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] hydrochloride;1428118-48-2;1428118-48-2;107220-28-0;107220-28-0;rac,cis-Cevimeline Hydrochloride Salt;rac,cis-Cevimeline Hydrochloride Salt;Cevimeline (hydrochloride);Cevimeline (hydrochloride);AKOS025311302;Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)oxathiolane), 2'-methyl-, hydrochloride, cis-(+-)-;AKOS025311302;cis-(+-)-2'-Methylspiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)oxathiolane) hydrochloride;Spiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)oxathiolane), 2'-methyl-, hydrochloride, cis-(+-)-;EN300-1273269;cis-(+-)-2'-Methylspiro(1-azabicyclo(2.2.2)octane-3,5'-(1,3)oxathiolane) hydrochloride;AKOS030526237;EN300-1273269;AKOS030526237;(+-)-cis-2-Methylspiro(1,3-oxathiolan-5,3')quinuclidine hydrochloride;(+-)-cis-2-Methylspiro(1,3-oxathiolan-5,3')quinuclidine hydrochloride;AF102B hydrochloride;Fks 508;AF102B hydrochloride;Snd 5008;Fks 508;CEVIMELINE, HYDROCHLORIDE SALT;Snd 5008;cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine]hydrochloride;CEVIMELINE, HYDROCHLORIDE SALT;cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine]hydrochloride
SMILES: C[C@H]1SC[C@@]2(CN3CCC2CC3)O1.Cl
Formula: C10H17NOs.HCl
M.Wt: 235.77402
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent M1-selective muscarinic agonist; decreases the K+-evoked [3H]ACh release from hippocampal synaptosomes and increases the K+-evoked [3H]DA release from striatal synaptosomes; attenuates cognitive dysfunctions in AF64A-treated rats with low toxicity.Other IndicationApproved
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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