Cas No.: | 500017-70-9 |
Chemical Name: | 2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]- |
Synonyms: | DC-517 |
SMILES: | OC(COC(CN1C2C=CC=CC=2C2C1=CC=CC=2)CN1C2C=CC=CC=2C2C=CC=CC1=2)CNC(C)C |
Formula: | C33H35N3O2 |
M.Wt: | 505.6499 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | DC_05 is a potent, selective, non-nucleoside DNA methyltransferase DNMT1 inhibitor with IC50 of 1.7 uM, displays significant selectivity toward other AdoMet-dependent protein methyltransferases; significantly inhibits cancer cell proliferation in vitro. |