KX2-391 mesylate| CAS 1080645-95-9

Cas No.:	1080645-95-9
Chemical Name:	Tirbanibulin Mesylate
Synonyms:	KX2-391 (Mesylate);2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide mesylate;KX01 Mesylate;Tirbanibulin (Mesylate);84AC3796WJ;Tirbanibulin mesylate (USAN);Tirbanibulin mesylate [USAN];N-Benzyl-2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]acetamide mesylate;Tirbanibulin mesylate;KX2391 Mesylate;BCP25173;D11692;2-(5-(4-(2-morpholinoethoxyl)phenyl)pyridin-2-yl)-N-benzylacetamide mesy;Tirbanibulin Mesylate
SMILES:	S(C([H])([H])[H])(=O)(=O)O[H].O1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2C([H])=C([H])C(C3=C([H])N=C(C([H])=C3[H])C([H])([H])C(N([H])C([H])([H])C3C([H])=C([H])C([H])=C([H])C=3[H])=O)=C([H])C=2[H])C([H])([H])C1([H])[H]
Formula:	C₂₇H₃₃N₃O₆S
M.Wt:	527.6324
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor; inhibits c-Src kinase with GI50s of 1.34 uM and 2.30 μM in NIH3T3/c-Src527F and SYF/c-Src527F cells, respectively; causes microtubule disruption in tumor cells; orally active.Solid TumorsPhase 2 Clinical

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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