SY-1365

  Cat. No.:  DC24205   Featured
Chemical Structure
1816989-16-8
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More than 5000 active chemicals with high quality for research!
Field of application
SY-1365 is a CDK7 inhibitor. In vitro, SY-1365 inhibited cell growth of many different cancer types at nanomolar concentrations.
Cas No.: 1816989-16-8
Synonyms: SY-1365,SY 1365,SY1365
SMILES: O=C(C1=NC=C(NC(/C=C/CN(C)C)=O)C=C1)N[C@]2(C)C[C@H](NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)CCC2
Formula: C31H35ClN8O2
M.Wt: 586.2572
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors[1].
Target: CDK7
References: [1]. Hu S,et al. Discovery and characterization of SY-1365, a selective, covalent inhibitor of CDK7. Cancer Res. 2019 May 7.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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