| DC47126 |
Corixetan
|
Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability. |
| DC46937 |
Seco-DUBA
|
Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs). |
| DC46260 |
DMEA-PNU-159682
|
DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682. |
| DC46252 |
Azonafide-PEABA
|
Azonafide-PEABA is a cytotoxic drug moiety. |
| DC46215 |
Tubulysin IM-1
|
Tubulysin IM-1 is an ADC Cytotoxin and tubulin binder used as anti-microtubule toxins. |
| DC45523 |
Seco-DUBA hydrochloride
|
Seco-DUBA hydrochloride is a toxin for ADC drug SYD985. |
| DC44785 |
7-MAD-MDCPT
|
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs). |
| DC44784 |
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin
|
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC). |
| DC42430 |
Trastuzumab emtansine
|
Trastuzumab emtansine (Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1 (derivative of maytansine). Trastuzumab emtansine can be used for the research of advanced breast cancer. |
| DC41129 |
Sandramycin
|
Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity. |
