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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

  Cat. No.:  DC48401   Featured
Chemical Structure
2388520-36-1
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Field of application
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4, linked via the cleavable ADC linker hydroxy-PEG10-acid.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2388520-36-1
Chemical Name: TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Synonyms: 4,​7,​10,​13,​16,​19,​22,​25,​28,​31-​Decaoxatritriacontan​oic acid, 33-​[4-​(4-​amino-​2-​butyl-​3H-​imidazo[4,​5-​c]​quinolin-​8-​yl)​-​1-​piperazinyl]​-​, hydrochloride (1:1)
SMILES: C12NC(CCCC)=NC1=C1C(=NC=2N)C=CC(N2CCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)CC2)=C1.Cl
Formula: C41H69ClN6O12
M.Wt: 873.47
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4, linked via the cleavable ADC linker hydroxy-PEG10-acid.
Target: Traditional Cytotoxic Agents
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References: [1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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