DEPC

  Cat. No.:  DC60076   Featured
Chemical Structure
51779-95-4
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More than 5000 active chemicals with high quality for research!
Field of application
DEPC, also known as DC22:1PC or SJN79954, is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. DEPC is a useful reagent in drug formulation study. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).
Cas No.: 51779-95-4
Chemical Name: 1,2-Dierucoyl-sn-glycero-3-phosphocholine
Synonyms: 3,5,9-Trioxa-4-phosphahentriacont-22-en-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(13Z)-1-oxo-13-docosen-1-yl]oxy]-, innersalt, 4-oxide, (7R,22Z)-;1,2-dierucoyl-sn-glycero-3-phosphocholine;3,5,9-Trioxa-4-phosphahentriacont-22-en-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(13Z)-1-oxo-13-docosen-1-yl]oxy]-, inn;L-Dierucoyl Lecithin;1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine;1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;(7R,22Z)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[[(13Z)-1-oxo-13-docosen-1-yl]oxy]-3,5,9-trioxa-4-phosphahentriacont-22-en-1-aminium 4-oxide, inner salt;1,2-Di(cis-13-docosenoyl)-sn-glycero-3-phosphocholine;DEPC;(R)-2,3-Bis(erucoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate;Dierucoyl Phosphatidylcholine;Dierucoyllecithin;22:1(13E));22:1(13Z));PC(22:1(13E);PC(22:1(13Z);PC(22:1(13E)/22:1(13E));PC(22:1/22:1);PC;1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine; PC(22:1(13Z)/22:1(13Z)); DEPC;1,2-Dierucoyl-sn-glycero-3-phosphocholine
SMILES: CCC/C=C\CCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCC/C=C\CCC
Formula: C52H100NO8P
M.Wt: 898.326100000001
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC58047 DSPE-PEG 2000 PEG2000-DSPE is used for creating micelles that are able to carry drugs with low solubility.
DC31000 LP-01 LP-01 is an ionizable cationic amino lipid (pKa = ~6.1). It has been used in the generation of lipid nanoparticles (LNPs). LNPs containing LP-01 and encapsulating both Cas9 mRNA and modified single-guide RNA (sgRNA) for the transport protein transthyretin (Ttr) induce gene editing in liver cells in mice in a dose-dependent manner resulting in reduced serum Ttr levels for at least 12 months.
DC60580 Endosidin5(ES5) Endosidine 5 (ES5), is one of the most potent small molecules interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm. The delivered mRNAs is greatly enhanced via inhibition of endocytic recycling in cells and in live mice. NAV2729 (NAV) and endosidin 5 (ES5), resulted in significant enhancement (1.5–2 folds) of LNP-mediated delivery of Fluc mRNAs. Incubation of NAV and ES5 together caused modest further increases in Fluc expression in comparison to the sole application of either compound.
DC80021 DSPE-PEG2000-MAL DSPE-PEG-MAL is one of the reactive phospholipid PEG reagents that can react with sulfhydryl group (mercaptan, -SH). DSPE (1, 2-distearyl-Sn-glycerol 3-phosphate ethanolamine) is a highly hydrophobic saturated 18C phospholipid.
DC57086 CL4H6 CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response[1][2].
DC60076 DEPC DEPC, also known as DC22:1PC or SJN79954, is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. DEPC is a useful reagent in drug formulation study. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).
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