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Pomalidomide-C6-COOH

  Cat. No.:  DC67677   Featured
Chemical Structure
2225940-50-9
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Field of application
Pomalidomide-C6-COOH is the pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC.
Cas No.: 2225940-50-9
Chemical Name: Pomalidomide-C6-COOH
Synonyms: 7-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]heptanoic acid;Pomalidomide-C6-COOH;7-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino}heptanoic acid;Pomalidomide 4'-alkylC6-acid;AT18120;7-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]heptanoic acid;AKOS040757698;2225940-50-9;7-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]heptanoic Acid;Pomalidomide-C6-acid;A1-49686;7-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]heptanoic acid;HY-131887;MFCD32063493;CS-0142247;SCHEMBL20242552;SY312558;7-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)heptanoic acid;TS-08942
SMILES: O=C1C2C(=CC=CC=2C(N1C1C(NC(CC1)=O)=O)=O)NCCCCCCC(=O)O
Formula: C20H23N3O6
M.Wt: 401.41
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC68008 Tris-GalNAc-β-Ala-PEG3-FITC The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007 Tris-GalNAc-β-Ala-PEG3-MAL A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006 Tri-GalNAc-PEG2000-DSPE Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005 Tris-GalNAc-PEG5-sulfo-NHS Ester An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004 Tris-GalNAc-β-Ala-PEG3-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003 Tris-GalNAc-β-Ala-PEG4-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002 Tris-β-GalNAc-β-Ala-PEG3-N3 (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001 Tris-β-GalNAc-PEG3-Azide Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000 Tris-GalNAc-β-Ala-PEG3-NH2
DC67999 Tris-GalNAc-Ahx-NH2
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