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Thalidomide-O-C6-NH2 hydrochloride

  Cat. No.:  DC67737   Featured
Chemical Structure
2245697-88-3
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More than 5000 active chemicals with high quality for research!
Field of application
Thalidomide-4-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET.
Cas No.: 2245697-88-3
Chemical Name: Thalidomide-O-C6-NH2 hydrochloride
Synonyms: Thalidomide-O-C6-NH2 hydrochloride;Thalidomide 4'-ether-alkylC6-amine;Thalidomide-O-C6-NH2 (hydrochloride);4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;4-(6-aminohexoxy)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride;Thalidomide-linker 4;Thalidomide - linker 4;ZB0190;AT31932;4-(6-Aminohexyloxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;4-[(6-Aminohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydroc;4-((6-Aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;-ether-alkylC6-amine;1H-?Isoindole-?1,?3(2H)?-?dione, 4-?[(6-?aminohexyl)?oxy]?-?2-?(2,?6-?dioxo-?3-?piperidinyl)?-?, hydrochloride;4-[(6-aminohexyl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;3-dione hydrochloride;4-((6-aminohexyl)oxy)-2-(2;EN300-7442256;1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride;2245697-88-3;4-[(6-Aminohexyl)oxy]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Hydrochloride;THALIDOMIDE-4-O-C6-NH2 HYDROCHLORIDE;PD086450;BP-28368;4-[(6-aminohexyl)oxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride;SY330203;AKOS037435230;DA-58503;Thalidomide-O-C6-Amine HCl;HY-135250B;CS-0119306;4-(6-aminohexoxy)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;hydrochloride;MFCD31689259;Z3476101063
SMILES: Cl[H].O(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C2C(N(C(C=21)=O)C1([H])C(N([H])C(C([H])([H])C1([H])[H])=O)=O)=O
Formula: C19H24ClN3O5
M.Wt: 409.86
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC68008 Tris-GalNAc-β-Ala-PEG3-FITC The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007 Tris-GalNAc-β-Ala-PEG3-MAL A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006 Tri-GalNAc-PEG2000-DSPE Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005 Tris-GalNAc-PEG5-sulfo-NHS Ester An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004 Tris-GalNAc-β-Ala-PEG3-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003 Tris-GalNAc-β-Ala-PEG4-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002 Tris-β-GalNAc-β-Ala-PEG3-N3 (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001 Tris-β-GalNAc-PEG3-Azide Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000 Tris-GalNAc-β-Ala-PEG3-NH2
DC67999 Tris-GalNAc-Ahx-NH2
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