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Pomalidomide-propargyl

  Cat. No.:  DC67819   Featured
Chemical Structure
2154342-25-1
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Field of application
Pomalidomide-propargyl contains an E3 ligand and a terminal alkyl group ready for click conjugation. Pomalidomide-propargyl is ready for conjugation to target proteins for PROTAC.
Cas No.: 2154342-25-1
Chemical Name: 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yl)amino-2,3-dihydro-1H-isoindole-1,3-dione
Synonyms: 2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindoline-1,3-dione;2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yl)amino-2,3-dihydro-1H-isoindole-1,3-dione;F71999;2154342-25-1;2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-ynylamino)isoindole-1,3-dione;EN300-26682875;2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindole-1,3-dione;DS-022385;2-(2,6-dioxo-3-piperidyl)-4-(prop-2-ynylamino)isoindoline-1,3-dione;SCHEMBL19585760;2-(2,6-dioxopiperidin-3-yl)-4-[(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-isoindole-1,3-dione;MFCD32063482;Pomalidomide-propargyl;SY275489;2-(2,6-Dioxo-3-piperidyl)-4-(2-propynylamino)isoindoline-1,3-dione
SMILES: O=C1C(CCC(N1)=O)N1C(C2C=CC=C(C=2C1=O)NCC#C)=O
Formula: C16H13N3O4
M.Wt: 311.30
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC68008 Tris-GalNAc-β-Ala-PEG3-FITC The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007 Tris-GalNAc-β-Ala-PEG3-MAL A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006 Tri-GalNAc-PEG2000-DSPE Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005 Tris-GalNAc-PEG5-sulfo-NHS Ester An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004 Tris-GalNAc-β-Ala-PEG3-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003 Tris-GalNAc-β-Ala-PEG4-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002 Tris-β-GalNAc-β-Ala-PEG3-N3 (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001 Tris-β-GalNAc-PEG3-Azide Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000 Tris-GalNAc-β-Ala-PEG3-NH2
DC67999 Tris-GalNAc-Ahx-NH2
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