CRBN ligand-877 |CAS 2244684-41-9| DC Chemicals

Cas No.:	2244684-41-9
Chemical Name:	(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Synonyms:	AT11466;(2S,4R)-1-((S)-2-AMINO-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(2-HYDROXY-4-(4-METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE HCL;(2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
SMILES:	Cl.S1C=NC(C)=C1C1C=CC(=C(C=1)O)CNC([C@@H]1C[C@H](CN1C([C@H](C(C)(C)C)N)=O)O)=O
Formula:	C₂₂H₃₁ClN₄O₄S
M.Wt:	483.02
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68008	Tris-GalNAc-β-Ala-PEG3-FITC	The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007	Tris-GalNAc-β-Ala-PEG3-MAL	A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006	Tri-GalNAc-PEG2000-DSPE	Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005	Tris-GalNAc-PEG5-sulfo-NHS Ester	An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004	Tris-GalNAc-β-Ala-PEG3-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003	Tris-GalNAc-β-Ala-PEG4-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002	Tris-β-GalNAc-β-Ala-PEG3-N3	(β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001	Tris-β-GalNAc-PEG3-Azide	Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000	Tris-GalNAc-β-Ala-PEG3-NH2
DC67999	Tris-GalNAc-Ahx-NH2