Cas No.: | 66-84-2 |
Chemical Name: | (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol hydrochloride |
Synonyms: | Glucosamine HCl; Chitosamine HCl; NSC 234443; NSC234443; NSC-234443; NSC 758; NSC758; NSC-758 |
SMILES: | Cl.OCC(C(C(C(C=O)N)O)O)O |
Formula: | C6H14ClNO5 |
M.Wt: | 215.63 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Glucosamine (hydrochloride) is a natural product.In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin. |