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Deferitrin

  Cat. No.:  DC7399   Featured
Chemical Structure
239101-33-8
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Field of application
Deferitrin (GT-56-252) is the first drug in a class of desferrithiocin-derived hexadentate iron chelators.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 239101-33-8
Chemical Name: Deferitrin
Synonyms: Deferitrin;(2Z,4S)-2-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)-4-methyl-1,3-thiazolidine-4-carboxylic acid;4'-Hydroxydesazadesferrithiocin;GT 56-252;UNII-T69Y9LDN44;4,5-Dihydro-2-(2,4-dihydroxyphenyl)-4-methylthiazol-4-(S)-carboxylic acid
SMILES: O=C([C@]1(C)N=C(C2=CC=C(O)C=C2O)SC1)O
Formula: C11H11NO4S
M.Wt: 253.274
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Deferitrin (GT-56-252), a desferrithiocin (DFT) analogue, is an orally active trident iron chelator. Deferitrin is used for chronic iron overload due to transfusional therapy. Deferitrin has the potential for beta-thalassemia major[1][2].
In Vitro: The iron-clearing efficiency (ICE) of Deferitrin (GT-56-252) in a non-iron-overloaded rodent model after oral (po) administration at 300 µmol/kg is shown to be 1.1%[1].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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