EI-1|ECAS 1418308-27-6|DC Chemicals

Cas No.:	1418308-27-6
Chemical Name:	EI1
Synonyms:	EI1;ei-1;6-cyano-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-1-(pentan-3-yl)-1H-indole-4-carboxamide;6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide;EI1; Ezh2 inhibitor;GTPL7013;BCP23699;2392AH;s7611;SB19343;AK547355;6-cyano-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-pentan-3-ylindole-4-carboxamide;1-(1-Ethylpropyl)-4-[[(2-oxo-4,6-d;1418308-27-6;1418308-27-6;1418308-27-6;NCGC00351776-01;NCGC00351776-01;NCGC00351776-01;Ezh2 inhibitor EI1;Ezh2 inhibitor EI1;Ezh2 inhibitor;EI-1;EI 1;Ezh2 inhibitor EI1;Ezh2 inhibitor;EI-1;EI 1;6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide;Ezh2 inhibitor;EI-1;EI 1;6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide;Q27077166;6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide;Q27077166;KB-145943;Q27077166;KB-145943;6-CYANO-N-[(4,6-DIMETHYL-2-OXO-1H-PYRIDIN-3-YL)METHYL]-1-(PENTAN-3-YL)INDOLE-4-CARBOXAMIDE;KB-145943;6-CYANO-N-[(4,6-DIMETHYL-2-OXO-1H-PYRIDIN-3-YL)METHYL]-1-(PENTAN-3-YL)INDOLE-4-CARBOXAMIDE;DTXSID101111134;6-CYANO-N-[(4,6-DIMETHYL-2-OXO-1H-PYRIDIN-3-YL)METHYL]-1-(PENTAN-3-YL)INDOLE-4-CARBOXAMIDE;DTXSID101111134;BRD-K91535048-001-01-2;DTXSID101111134;BRD-K91535048-001-01-2;AKOS030526508;BRD-K91535048-001-01-2;AKOS030526508;C72647;AKOS030526508;C72647;PFHDWRIVDDIFRP-UHFFFAOYSA-N;C72647;GLXC-04158;PFHDWRIVDDIFRP-UHFFFAOYSA-N;PFHDWRIVDDIFRP-UHFFFAOYSA-N;NCGC00351776-03;GLXC-04158;GLXC-04158;CCG-268533;NCGC00351776-03;NCGC00351776-03;CS-1654;CCG-268533;CCG-268533;HY-15573;CS-1654;CS-1654;DA-73049;HY-15573;HY-15573;EX-A2431;DA-73049;DA-73049;AC-36069;EX-A2431;EX-A2431;AS-55788;AC-36069;AC-36069;SCHEMBL16197843;AS-55788;AS-55788;SCHEMBL16197843;SCHEMBL16197843
SMILES:	O=C(C1C([H])=C(C#N)C([H])=C2C=1C([H])=C([H])N2C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N([H])C([H])([H])C1C(N([H])C(C([H])([H])[H])=C([H])C=1C([H])([H])[H])=O
Formula:	C₂₃H₂₆N₄O₂
M.Wt:	390.4781
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

EI1 is a potent and selective small molecule inhibitor of EZH2 with IC50 values of 15 nM and 13 nM for wild type EZH2 and EZH2 Y641F mutant, respectively. IC50 Value: 15±2 nM (EZH2 wild type); 13±3 nM (EZH2 Y641F mutant type) For the detailed information of EI-1, the solubility of EI-1 in water, the solubility of EI-1 in DMSO, the solubility of EI-1 in PBS buffer, the animal experiment (test) of EI-1, the cell expriment (test) of EI-1, the in vivo, in vitro and clinical trial test of EI-1, the EC50, IC50,and affinity,of EI-1, Please contact DC Chemicals.

MSDS

COA

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2018-0101

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