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Eptifibatide GMP grade

  Cat. No.:  DC37766   Featured
Chemical Structure
188627-80-7
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More than 5000 active chemicals with high quality for research!
Field of application
Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation. Eptifibatide prevents binding of the adhesion proteins fibrinogen and von Willebrand factor to GPIIb/IIIa on the surface of activated platelets to prevent aggregation and thrombus formation. It inhibits ADP-induced citrated blood aggregation (IC50 = 0.11-0.22 μg/ml) in vitro and in vivo (IC50 = 52 μg/ml in porcine plasma). Formulations containing eptifibatide have been used to reduce risk of thrombolysis in myocardial infarction in patients undergoing percutaneous coronary intervention.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 188627-80-7
Chemical Name: Eptifibatide
Synonyms: Eptifibatide;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;{MPA}{HAR}GDWPC-NH2;MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDE BRIDGE, MPA1-CYS6);Intrifiban;3-Mercaptopropionyl-HoMoarg-Gly-Asp-Trp-Pro-Cys-NH2;N6-(AMinoiMinoMethyl)-N2-(3-Mercapto-1-oxopropyl)-L-lysylglycyl-L-.alpha.-aspartyl-L-tryptophyl-L-prolyl-L-cysteinaMide Cyclic (16)-Disulfide;Eptifibatide impurity;Integrilin;Eptifibatide Acetate;C35H49N11O9S2;NA8320J834;DSSTox_RID_81810;DSSTox_CID_26673;DSSTox_GSID_46673;S(1),S(6)-cyclo[N(6)-carbamimidoyl-N(2)-(3-sulfanylpropanoyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide];N(6)-amidino-N(2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide;[(3R,11;AKOS015895205;NCGC00167505-01;EPTIFIBATIDE [INN];NCGC00263524-01;Eptifibatide Accord (generic);[(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid;EX-A3111;GTPL6585;Tox21_112503_1;EPTIFIBATIDE (MART.);N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide;L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-;CHEMBL1174;Sch-60936;7H-Pyrrolo(2,1-g)(1,2,5,8,11,14,17,20)dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-(4-((aminoiminomethyl)amino)butyl)docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-, (3R,11S,17S,20S,25aS)-;CHEBI:291902;eptifibatidum;C73610;BDBM50092098;L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic (1-6)-disulfide;Eptifibatide [INN:BAN];HY-B0686;EPTIFIBATIDE [ORANGE BOOK];NCGC00167505-03;Tox21_112503;188627-80-7;DTXCID5026673;C68-22;A-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1 inverted exclamation marku6)-disulfide;EPTIFIBATIDE [EMA EPAR];epifibratide;((3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo(2,1-g)(1,2,5,8,11,14,17,20)dithiahexaazacyclotricosin-17-yl)acetic acid;CCG-270517;Q2295855;EPTIFIBATIDE [MI];SCHEMBL15781;Eptifibatide acetate?;AKOS025147403;EPTIFIBATIDE [USAN];EPTIFIBATIDE [VANDF];157630-07-4;1-[(1R)-1-Phenylethyl]-1Himidazole-5-carboxylic acid ethyl ester; (+)-Ethyl 1-(;HSDB 8313;UNII-NA8320J834;CZKPOZZJODAYPZ-LROMGURASA-N;2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid;EPTIFIBATIDE [MART.];[22-Carbamoyl-14-(4-guanidino-butyl)-5-(1H...
SMILES: S1C([H])([H])[C@@]([H])(C(N([H])[H])=O)N([H])C([C@]2([H])C([H])([H])C([H])([H])C([H])([H])N2C([C@]([H])(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])/N=C(\N([H])[H])/N([H])[H])N([H])C(C([H])([H])C([H])([H])S1)=O)=O)=O)=O)=O)=O
Formula: C35H49N11O9S2
M.Wt: 831.9619
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_20076_DC37766
COA
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Cat. No. Product name Field of application
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