Cas No.: | 59729-37-2 |
Chemical Name: | Fexinidazole |
Synonyms: | 1-Methyl-2-((4-(methylthio)phenoxy)methyl)-5-nitro-1H-imidazole;Fexinidazole;1H-Imidazole,1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-;1-Methyl-2-((4-(methylthio)phenoxy)-methyl)-5-nitro-1H-imidazole;1-methyl-2-[(4-methylsulfanylphenoxy)methyl]-5-nitroimidazole;1-methyl-2-(4-methylsulfanyl-phenoxymethyl)-5-nitro-1H-imidazole;1-methyl-2-(4-methylthiophenyl-oxymethyl)-5-nitro-imidazole;AC1L2AGG;Fexinidazol;Fexinidazol [INN-Spanish];Fexinidazole [INN];Fexinidazolum;Fexinidazolum [INN-Latin];HOE 239;HOE-239;1-Methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole;306ERL82IR;Fexinidazole (INN);AK116408;fexinidazole[inn];MLS006010234;M |
SMILES: | O=[N+](C1=CN=C(COC2=CC=C(SC)C=C2)N1C)[O-] |
Formula: | C12H13N3O3S |
M.Wt: | 279.3149 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologically relevant active metabolites in vivo are the sulfoxide and sulfone.. For the detailed information of Fexinidazole (HOE-239), the solubility of Fexinidazole (HOE-239) in water, the solubility of Fexinidazole (HOE-239) in DMSO, the solubility of Fexinidazole (HOE-239) in PBS buffer, the animal experiment (test) of Fexinidazole (HOE-239), the cell expriment (test) of Fexinidazole (HOE-239), the in vivo, in vitro and clinical trial test of Fexinidazole (HOE-239), the EC50, IC50,and affinity,of Fexinidazole (HOE-239), Please contact DC Chemicals. |