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HPPH

  Cat. No.:  DC31272   Featured
Chemical Structure
149402-51-7
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More than 5000 active chemicals with high quality for research!
Field of application
Photochlor, also known as HTTP, is a lipophilic, second-generation, chlorin-based photosensitizer. Upon intravenous administration, HPPH selectively accumulates in the cytoplasm of cancer or pre-cancerous cells. When laser light is applied, a photodynamic reaction between HPPH and oxygen occurs, resulting in the production of cytotoxic free radicals and singlet oxygen and free radical-mediated cell death. Compared to the first-generation photosensitizer porfimer sodium, HPPH shows improved pharmacokinetic properties and causes only mild skin photosensitivity which declines rapidly within a few days after administration.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 149402-51-7
Chemical Name: HPPH
Synonyms: 3-Phorbinepropanoicacid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-;2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a;3-{(3S,4S)-14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-24,25-dihydrophorbin-3-yl}propanoic acid;(3S,4S)-14-Ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid;2-[1'-(Hexyloxy)ethyl]-2-devinylpyropheophorbide A;3-Devinyl-3-(1'-hexyloxy)ethylpyropheophorbide A;Photochlor;Sulcardine;Photochlor (HPPH);14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbine propanoic acid;3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18 -tetramethyl-20-oxo-, (3S,4S)-;CID 135565955;HPPH;DTXSID501028872;DTXSID501028872;DTXSID501028872;UNII-DOB7Y3RSX0;UNII-DOB7Y3RSX0;UNII-DOB7Y3RSX0;PD121997;PD121997;PD121997;2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a;2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a;2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a;3-Phorbinepropanoic acid, 14-ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-;3-Phorbinepropanoic acid, 14-ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-;3-Phorbinepropanoic acid, 14-ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-;SCHEMBL20834922;SCHEMBL20834922;SCHEMBL20834922;DOB7Y3RSX0;DOB7Y3RSX0;DOB7Y3RSX0;SCHEMBL12722713;SCHEMBL12722713;SCHEMBL12722713;DA-54084;DA-54084;DA-54084;CS-0007752;CS-0007752;CS-0007752;CHEMBL500853;CHEMBL500853;CHEMBL500853;AC-35598;AC-35598;AC-35598;HY-13722;HY-13722;Q4596815;HY-13722;2-(1-HEXYLOXYETHYL)-2-DEVINYLPYROPHEOPHORBIDE A;Q4596815;Q4596815;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid;2-(1-HEXYLOXYETHYL)-2-DEVINYLPYROPHEOPHORBIDE A;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid;2-(1-HEXYLOXYETHYL)-2-DEVINYLPYROPHEOPHORBIDE A;3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-;3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-;ZFA40251;14-Ethyl-9-(1-(hexyloxy)ethyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid;ZFA40251;3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)-;3-Phorbinepropanoic acid, 14-ethyl-9-[1-(hexyloxy)ethyl]-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-;3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)-;149402-51-7;149402-51-7;ZFA40251;CHEMBL5170755;CHEMBL5170755;2-(1-HEXYLOXYETHYL)-2-DEVINYLPYROPHEOPHORBIDE-A;3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)-;2-(1-HEXYLOXYETHYL)-2-DEVINYLPYROPHEOPHORBIDE-A;3-[(21S,22S)-11-ethyl-16-(1-hexoxyethyl)-4-hydroxy-12,17,21,26-tetramethyl-7,23,24,25-tetrazahexacyclo[18.2.1.15,8.110,13.115,18.02,6]hexacosa-1,4,6,8(26),9,11,13(25),14,16,18(24),19-undecaen...
SMILES: OC1=C2C(C)=C3C=C4C(CC)=C(C)C(C=C5C([C@H](C)OCCCCCC)=C(C)C(C=C6[C@@H](C)[C@H](CCC(=O)O)C(=C(C2=N3)C1)N6)=N5)=N4 |t:6,14,29,39|
Formula: C39H48N4O4
M.Wt: 636.82
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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