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Hydroxy-PEG10-Boc

  Cat. No.:  DC29197   Featured
Chemical Structure
778596-26-2
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Field of application
Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel or docetaxel.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 778596-26-2
Chemical Name: HO-PEG10-tBu
Synonyms: HO-PEG10-CH2CH2COOtBu;HO-PEG10-tBu;Hydroxy-PEG10-t-butyl ester;tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate
SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Formula: C27H54O13
M.Wt: 586.71000
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel or docetaxel.
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References: [1]. Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent [2]. Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5.
MSDS
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MSDS_13245_DC29197_778596-26-2
COA
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