Isochlorogenic acid C

  Cat. No.:  DC23034   Featured
Chemical Structure
57378-72-0
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More than 5000 active chemicals with high quality for research!
Field of application
4,5-Dicaffeoylquinic acid ( Isochlorogenic acid C) possesses potent hepatoprotective and anti-HBV effects.IC50 value:Target: Anti-hepatitis natural produce.In vitro: To study anti-hepatitis effect of isochlorogenic acid C, anti-apoptotic and anti-injury properties of test compound were evaluated. The results showed that test compound at concentrations of 10 to 100 μg/ml significantly reduced the caspase-3 and transformed growth factor β1 (TGFβ1) levels of the D-GalN-challenged hepatocytes. Also, test compound improved markedly cell viability of the D-GalN-injured hepatocytes and produced a maximum protection rate of 47.28% at a concentration of 100 μg/ml. Furthermore, test compound significantly inhibited productions of HBsAg and HBeAg. Its maximum inhibitory rates on the HBsAg and HBeAg expressions were 86.93 and 59.79%, respectively. In addition, test compound significantly induced the HO-1 expression of HepG2.2.15 cells [1]. In vivo:
Cas No.: 57378-72-0
Chemical Name: 4,5-Di-O-caffeoylquinic acid
Synonyms: Isochlorogenic acid C;4,5-Dicaffeoylquinic acid;Isochlorogenic acid C(4,5);3,4-O-DICAFFEOYL QUINIC ACID;4,5-Dinitrophenanthren;4,5-di-O-caffeoylquinic acid;4,5-di-O-trans-caffeoyl-D-quinic acid;4,5-di-O-trans-caffeoylquininc acid;Phenanthrene,4,5-dinitro;{ "\"0\"": "4,5-Dicaffeoylquinic acid" };E57A0DKE0B;4,5-DCQA;4,5-dicaffeoyl quinic acid;(1R,3R,4S,5R)-3,4-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,5-dihydroxy-cyclohexanecarboxylic acid;Isochlorogenic acid I;3,4-di-O-caffeoylquinicacid;3,4-DICQA;Isochlorogenic acid C(4,5');3,4-DCQA;BDBM50056908;9573AF
SMILES: O(C(/C(/[H])=C(\[H])/C1C([H])=C([H])C(=C(C=1[H])O[H])O[H])=O)[C@]1([H])C([H])([H])[C@@](C(=O)O[H])(C([H])([H])[C@]([H])([C@]1([H])OC(/C(/[H])=C(\[H])/C1C([H])=C([H])C(=C(C=1[H])O[H])O[H])=O)O[H])O[H]
Formula: C25H24O12
M.Wt: 516.4509
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: For the detailed information of Isochlorogenic acid C, the solubility of Isochlorogenic acid C in water, the solubility of Isochlorogenic acid C in DMSO, the solubility of Isochlorogenic acid C in PBS buffer, the animal experiment(test) (test) of Isochlorogenic acid C, the cell expriment (test) of Isochlorogenic acid C, the in vivo, in vitro and clinical trial test of Isochlorogenic acid C, the EC50, IC50,and Affinity of Isochlorogenic acid C,, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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