Cas No.: | 22071-15-4 |
SMILES: | OC(C(C1C=CC=C(C(C2C=CC=CC=2)=O)C=1)C)=O |
Formula: | C16H14O3 |
M.Wt: | 254.28 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Ketoprofen (Actron) is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. Ketoprofen 50 and 100 mg and of paracetamol with diclofenac were associated with lower pain scores than paracetamol alone. In the study of paracetamol and ketoprofen, the combination reduced pain scores both at rest and on movement after disc surgery compared with paracetamol alone. In a study involving spinal fusion surgery, the combination of propacetamol and ketoprofen 100 mg improved pain scores assessed by VAS pain intensity differences. |