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LC-PEG8-SPDP

  Cat. No.:  DC28485   Featured
Chemical Structure
1252257-56-9
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Field of application
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1252257-56-9
Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-oxo-1-(pyridin-2-yldisulfanyl)-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oate
Synonyms: 2,5-dioxopyrrolidin-1-yl 3-oxo-1-(pyridin-2-yldisulfanyl)-7,10,13,16,19,22,25,28-octaoxa-4-azahentriacontan-31-oate
SMILES: O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O)CCSSC1C=CC=CN=1
Formula: C31H49N3O13S2
M.Wt: 735.863067388535
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Target: Cleavable
References: [1]. Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.
MSDS
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MSDS_12538_DC28485_1252257-56-9
COA
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Cat. No. Product name Field of application
DC39235 Fmoc-Val-Ala-PAB-OH Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC46131 Acid-C3-SSPy Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4, a drug-linker conjugate for ADC.
DC43960 MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC42440 Fmoc-Gly-Gly-Phe-OH Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41151 Boc-Dap-NE Boc-Dap-NE, a dipeptide, is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41150 Fmoc-3VVD-OH Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41143 MC-Gly-Gly-Phe-Gly MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
DC40831 Fmoc-Val-Ala-PAB-PNP Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40614 Maleimide-DOTA Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC29217 N-Boc-diethanolamine N-Boc-diethanolamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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