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Lofepramine

  Cat. No.:  DC28447   Featured
Chemical Structure
23047-25-8
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More than 5000 active chemicals with high quality for research!
Field of application
Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 23047-25-8
Chemical Name: Lofepramine
Synonyms: Ethanone,1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-;Lofepramine;1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone;Ethanone, 1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-;AKOS024457158;Lofepramine (INN);GTPL7551;1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one;Lofepramina [INN-Spanish];4'-chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin5-yl)propyl)methylamino)acetophenone;Lofepramine- Bio-X;Tymelyt (Salt/Mix);HY-12390;FT-0670832;J-014957;CHEMBL87708;Ethanone, 1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)-;HMS3715L16;A854424;4'-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon;LOFEPRAMINE [MI];DTXSID2023220;Lofepramin hydrochloride (Salt/Mix);AB00698521-05;D08140;CHEBI:47782;NCGC00166397-03;Lopramine;Lofepraminum;BDBM82437;Amplit;LOFEPRAMINE [INN];Acetophenone, 4'-chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin5-yl)propyl)methylamino)-;1-(4-chlorophenyl)-2-{[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamino}ethanone;UNII-OCA4JT7PAW;LOFEPRAMINE [HSDB];HMS3677F21;NCGC00166397-01;Q368941;NCGC00166397-02;4'-CHLORO-2-((3-(10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPIN-5-YL)PROPYL)METHYLAMINO)ACETOPHENONE;BL164630;Gamanil (Salt/Mix);1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone;1-(4-chlorophenyl)-2-{[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl](methyl)amino}ethanone;LOFEPRAMINE [WHO-DD];EINECS 245-396-8;OCA4JT7PAW;Lofepramina;CAS_23047-25-8;LOFEPRAMINE [JAN];Lomont;HMS3413F21;CS-0011244;Leo 640;HSDB 7184;Lofepramine [INN:BAN];Lofepraminum [INN-Latin];Z2681890859;Gamanil;23047-25-8;CCG-221257;4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]acetophenone;HMS3269O19;DB13411;NS00004691;N-Methyl-N(4-chlorobenzoylmethyl)-3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propylamine hydrochloride;SAPNXPWPAUFAJU-UHFFFAOYSA-N;Timelit (Salt/Mix);SCHEMBL35028;1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl](methyl)amino]ethanone #;Gamonil (Salt/Mix);US8629135, SW-06;NSC_3947;DB 2182;L000944;G12703;N-methyl-N-(4-chlorobenzoylmethyl)-3-(10,11-dihydro-5H-dibenzo;1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)propyl)methylamino)ethanone;4'-Chloro-2-;1-(4-chlorophenyl)-2-(3-(5,6-dihydrobenzo(b)(1)benzazepin-11-yl)propyl-methylamino)ethanone;1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)propyl)(methyl)amino)ethanone;N06AA07;Lofepramina (INN-Spanish);BRD-K82147103-003-05-6;DA-54990;Amplit (TN);DTXCID303220;N-Methyl-N(4-chlorobenzoylmethyl)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)propylamine hydrochloride;Gamanil (United Kingdom);BRD-K82147103-001-02-7;1-(4-C...
SMILES: CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
Formula: C26H27N2OCl
M.Wt: 418.95838
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12500_DC28447_23047-25-8
COA
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Cat. No. Product name Field of application
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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