DC47776 |
Millmerranone A
|
Millmerranone A shows the acetylcholinesterase inhibitory property. |
DC47775 |
Chikusetsusaponin Ib
|
Chikusetsusaponin Ib has anti-Alzheimer's disease activity and is a potent AChE inhibitor. |
DC47774 |
Cyclopenin
|
Cyclopenin ((±)-Isocyclopenine) is a racemate. |
DC47773 |
Cyclanoline chloride
|
Cyclanoline (chloride) shows cholinesterase inhibitory activity. |
DC47772 |
Isonaringin
|
Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE. |
DC47239 |
Zanapezil free base
|
Zanapezil (TAK-147) free base is a potent, reversible and selective acetylcholine esterase (AChE) inhibitor. Zanapezil free base shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex (IC50=51.2 nM). Zanapezil free base shows a moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. Zanapezil free base can be used for the research of early stages of Alzheimer's disease (AD). |
DC46568 |
Acotiamide D6
|
Acotiamide D6 is a deuterium labeled Acotiamide. Acotiamide is an orally active and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia. |
DC46069 |
Echimidine N-oxide
|
Echimidine N-oxide, a pyrrolizidine alkaloid, has acetylcholinesterase (AChE) inhibitory activity (IC50=0.347 mM). |
DC45995 |
Manghaslin
|
Manghaslin is a flavonoid glycoside with anti-inflammatory activities. Manghaslin shows inhibitory activity against AChE with an IC50 of 94.92 µM. |
DC44782 |
O-Desmethyl Galanthamine
|
O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM. |