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N-Desmethyl Apalutamide

  Cat. No.:  DC28811  
Chemical Structure
1332391-11-3
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Field of application
N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1332391-11-3
SMILES: O=C(N)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43CCC4)C=C1F
Formula: C20H13F4N5O2S
M.Wt: 463.41
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12863_DC28811_1332391-11-3
COA
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Cat. No. Product name Field of application
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