Nilutamide|cas 63612-50-0|supplier DC Chemicals

Cas No.:	63612-50-0
SMILES:	O=C(C1(C)C)N(C(N1)=O)C2=CC=C([N+]([O-])=O)C(C(F)(F)F)=C2
Formula:	C₁₂H₁₀F₃N₃O₄
M.Wt:	317.22
Purity:	99%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Nilutamide is an antiandrogen medication used in the treatment of advanced stage prostate cancer. Nilutamide blocks the androgen receptor, preventing its interaction with testosterone. Because most prostate cancer cells rely on the stimulation of the androgen receptor For growth and survival, nilutamide can prolong life in men with prostate cancer. Nilutamide is marketed under the name Nilandron in the United States and under the name Anandron in Canada. NILANDRON® tablets contain nilutamide, a nonsteroidal, orally active antiandrogen having the chemical name 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. Nilutamide is a microcrystalline, white to practically white powder with a molecular weight of 317.25. Its molecular Formula is C12H10F3N3O4. It is freely soluble in ethyl acetate, acetone, chloro Form, ethyl alcohol, dichloromethane, and methanol. It is slightly soluble in water [ < 0.1% W/V at 25°C (77°F)]. It melts between 153°C and 156°C (307.4°F and 312.8°F). Each NILANDRON tablet contains 150 mg of nilutamide. Other ingredients in NILANDRON tablets are corn starch, lactose, povidone, docusate sodium, magnesium stearate, and talc. For the detailed information about the solubility of Nilutamide in water, the solubility of Nilutamide in DMSO, the solubility of Nilutamide in PBS buffer, the animal experiment（test） of Nilutamide, the in vivo,in vitro and clinical trial test of Nilutamide, the cell experiment（test） of Nilutamide, the IC50, EC50 and Affinity of Nilutamide , please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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