PF3845yne(PF 3845yne)|analogues of PF3845|DC Chemicals

Cas No.:	1196109-53-1
Chemical Name:	4-[[3-[(5-Ethynyl-2-pyridinyl)oxy]phenyl]methyl]-N-3-pyridinyl-1-piperidinecarboxamide
Synonyms:	PF3845yne,PF3845 yne,PF3845-yne,PF 3845 yne
SMILES:	C#CC1=CN=C(C=C1)OC2=CC=CC(=C2)CC3CCN(CC3)C(=O)NC4=CN=CC=C4
Formula:	C₂₅H₂₄N₄O₂
M.Wt:	412.48366
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Both PF3845yne and JP104 selectively reacted with a single brain protein, which was confirmed to be FAAH based on its absent from FAAH(−/−) mice. In liver, however, PF3845yne and JP104 showed strikingly different profiles, with the former agent once again showing selective reactivity with FAAH and the latter inhibitor labeling a number of proteins. These data indicate that PF-3845 inhibits FAAH in vivo with exceptional efficacy and selectivity. For the detailed information of PF3845 yne, the solubility of PF3845 yne in water, the solubility of PF3845 yne in DMSO, the solubility of PF3845 yne in PBS buffer, the animal experiment (test) of PF3845 yne, the cell expriment (test) of PF3845 yne, the in vivo, in vitro and clinical trial test of PF3845 yne, the EC50, IC50,and affinity,of PF3845 yne, For the detailed information of PF3845 yne, the solubility of PF3845 yne in water, the solubility of PF3845 yne in DMSO, the solubility of PF3845 yne in PBS buffer, the animal experiment (test) of PF3845 yne, the cell expriment (test) of PF3845 yne, the in vivo, in vitro and clinical trial test of PF3845 yne, the EC50, IC50,and affinity,of PF3845 yne, Please contact DC Chemicals.

MSDS

COA

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2018-0101

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