PF-429242(PF429242)|S1P inhibitor|DC Chemicals

Cas No.:	947303-87-9
Chemical Name:	4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide
Synonyms:	PF-429242,PF429242
SMILES:	C(N(CCC1=CC=CC=C1OC)[C@H]1CCNC1)(=O)C1=CC=C(CN(CC)CC)C=C1.Cl.Cl
Formula:	C₂₅H₃₅N₃O₂^.₂HCl
M.Wt:	482.49
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PF-429242 is a potent inhibitor of S1P (cellular proprotein convertase sterol regulatory element-binding protein (SREBP) site 1 protease) that reduces expression levels of hepatic SREBP target genes and lower rates of cholesterol and fatty acid synthesis in mice. PF-429242 is a potent antiviral agent against prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV in cultured cells. PF-429242 efficiently prevented the processing of GPC from the LCMV and LASV. PF-429242 is expected to be active against CCHFV.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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PF 429242