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Pembrolizumab Biosimilar(Anti-PDCD1 / PD-1 / CD279 Reference Antibody)

  Cat. No.:  A016   Featured
Chemical Structure
1374853-91-4
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More than 5000 active chemicals with high quality for research!
Field of application
Pembrolizumab (anti-PD-1) is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1374853-91-4
pH value: Corresponds to reference standard： PASS
Non-reduced CE-SDS: 98.1%
SEC-HPLC: 99.7%
Isoelectric Point: Corresponds to reference standard:PASS
Bacterial Endotoxins Test: ＜1 EU/ml
Exogenous Residual DNA: ＜1 pg/mg
Residual protein A: ＜1 ng/mg
Biological Activity: Compared with standard, the range of biological activity is 113%
Osmolality: Corresponds to reference standard: PASS
Peptide mapping: Corresponds to reference standard: PASS
N-terminal sequence: Corresponds to reference standard:PASS
Description: Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.
References: [1]. Schachter J, et al. Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006). Lancet. 2017 Aug 16. pii: S0140-6736(17)31601-X.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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