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Propargyl-PEG2-acid

  Cat. No.:  DC28391   Featured
Chemical Structure
1859379-85-3
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Field of application
Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1859379-85-3
Chemical Name: Propargyl-PEG2-acid
Synonyms: Propargyl-PEG2-acid
SMILES: O(C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])OC([H])([H])C#C[H]
Formula: C8O4H12
M.Wt: 172.1785
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target: Non-cleavable
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References: [1]. Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.
MSDS
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MSDS_12444_DC28391_1859379-85-3
COA
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Cat. No. Product name Field of application
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DC42440 Fmoc-Gly-Gly-Phe-OH Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC41143 MC-Gly-Gly-Phe-Gly MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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DC40614 Maleimide-DOTA Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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