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Ro 20-0657/000

  Cat. No.:  DC28080   Featured
Chemical Structure
29606-06-2
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More than 5000 active chemicals with high quality for research!
Field of application
Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 29606-06-2
Chemical Name: a-Hydroxy Trimethoprim (Impurity)
Synonyms: 5-Pyrimidinemethanol,2,4-diamino-a-(3,4,5-trimethoxyphenyl)-;α-Hydroxy Trimethoprim (Impurity);(2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanol;TRIMETHOPRIM IMP. C (EP): (RS)-(2,4-DIAMINOPYRIMIDIN-5-YL) (3,4,5-TRIMETHOXYPHENYL)METHANOL, CRM STANDARD;Trimethoprim Impurity C;000;2,4-Diamino-5-(a-hydroxy-3,4,5-trimethoxybenzyl)pyrimidine;Racemic a-(2,4-diamino-5-pyrimidyl)-3,4,5-trimethoxybenzylalcohol;Ro 20-0657;Ro 20-0657/000;AKOS040736683;(RS)-(2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanol;(2,4-DIAMINOPYRIMIDIN-5-YL)(3,4,5-TRIMETHOXYPHENYL)METHANOL;(+/-)- .ALPHA.-(2,4-DIAMINO-5-PYRIMIDYL)-3,4,5-TRIMETHOXYBENZYL ALCOHOL;Calpha-Hydroxytrimethoprom;NS00003521;HY-100622;TRIMETHOPRIM IMPURITY C [EP IMPURITY];Racemic alpha-(2,4-diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl alcohol;RO-20-0657/000;CHEMBL1260;ALPHA-HYDROXYTRIMETHOPRIM;DTXSID401347744;Q27266230;29606-06-2;2,4-Diamino-alpha-(3,4,5-trimethoxyphenyl)-5-pyrimidinemethanol;BDBM50470946;7439XP501F;BCP29947;5-PYRIMIDINEMETHANOL, 2,4-DIAMINO-.ALPHA.-(3,4,5-TRIMETHOXYPHENYL)-;alpha-Hydroxytrimetoprim;(c) paragraph sign-Hydroxy Trimethoprim (Impurity);Racemic (c) paragraph sign-(2,4-Diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl Alcohol;Trimethoprim Imp. C (EP); (RS)-(2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanol; 62U70 ; GW 340134X; Ph Eur Trimethoprim Impurity C; Trimethoprim Impurity C;5-Pyrimidinemethanol, 2,4-diamino-alpha-(3,4,5-trimethoxyphenyl)-;Trimethoprim impurity C [EP];alpha-Hydroxy Trimethoprim (Impurity);a-Hydroxy Trimethoprim (Impurity);(2, 4-diaminopyrimidin-5-yl)-(3, 4, 5-trimethoxyphenyl)methanol;(+/-)- alpha-(2,4-Diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl alcohol;CS-0019803;UNII-7439XP501F;.ALPHA.-HYDROXYTRIMETHOPRIM;A876423;RACEMIC .ALPHA.-(2,4-DIAMINO-5-PYRIMIDYL)-3,4,5-TRIMETHOXYBENZYL ALCOHOL;G63608;DA-57474;ARD173319;Trimethoprim Impurity C (Ca-Hydroxy-TMP)
SMILES: COC1=CC(C(C2=CN=C(N)N=C2N)O)=CC(OC)=C1OC
Formula: C14H18N4O4
M.Wt: 306.31712
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12136_DC28080_29606-06-2
COA
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Cat. No. Product name Field of application
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DC46373 TP0586532 TP0586532 is a non-hydroxamate LpxC inhibitor (IC50=0.101 μM). TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains.
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