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Ro 20-0657/000

  Cat. No.:  DC28080   Featured
Chemical Structure
29606-06-2
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More than 5000 active chemicals with high quality for research!
Field of application
Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 29606-06-2
Chemical Name: a-Hydroxy Trimethoprim (Impurity)
Synonyms: 5-Pyrimidinemethanol,2,4-diamino-a-(3,4,5-trimethoxyphenyl)-;α-Hydroxy Trimethoprim (Impurity);(2,4-diaminopyrimidin-5-yl)-(3,4,5-trimethoxyphenyl)methanol;TRIMETHOPRIM IMP. C (EP): (RS)-(2,4-DIAMINOPYRIMIDIN-5-YL) (3,4,5-TRIMETHOXYPHENYL)METHANOL, CRM STANDARD;Trimethoprim Impurity C;000;2,4-Diamino-5-(a-hydroxy-3,4,5-trimethoxybenzyl)pyrimidine;Racemic a-(2,4-diamino-5-pyrimidyl)-3,4,5-trimethoxybenzylalcohol;Ro 20-0657;Ro 20-0657/000;AKOS040736683;(RS)-(2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanol;(2,4-DIAMINOPYRIMIDIN-5-YL)(3,4,5-TRIMETHOXYPHENYL)METHANOL;(+/-)- .ALPHA.-(2,4-DIAMINO-5-PYRIMIDYL)-3,4,5-TRIMETHOXYBENZYL ALCOHOL;Calpha-Hydroxytrimethoprom;NS00003521;HY-100622;TRIMETHOPRIM IMPURITY C [EP IMPURITY];Racemic alpha-(2,4-diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl alcohol;RO-20-0657/000;CHEMBL1260;ALPHA-HYDROXYTRIMETHOPRIM;DTXSID401347744;Q27266230;29606-06-2;2,4-Diamino-alpha-(3,4,5-trimethoxyphenyl)-5-pyrimidinemethanol;BDBM50470946;7439XP501F;BCP29947;5-PYRIMIDINEMETHANOL, 2,4-DIAMINO-.ALPHA.-(3,4,5-TRIMETHOXYPHENYL)-;alpha-Hydroxytrimetoprim;(c) paragraph sign-Hydroxy Trimethoprim (Impurity);Racemic (c) paragraph sign-(2,4-Diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl Alcohol;Trimethoprim Imp. C (EP); (RS)-(2,4-Diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanol; 62U70 ; GW 340134X; Ph Eur Trimethoprim Impurity C; Trimethoprim Impurity C;5-Pyrimidinemethanol, 2,4-diamino-alpha-(3,4,5-trimethoxyphenyl)-;Trimethoprim impurity C [EP];alpha-Hydroxy Trimethoprim (Impurity);a-Hydroxy Trimethoprim (Impurity);(2, 4-diaminopyrimidin-5-yl)-(3, 4, 5-trimethoxyphenyl)methanol;(+/-)- alpha-(2,4-Diamino-5-pyrimidyl)-3,4,5-trimethoxybenzyl alcohol;CS-0019803;UNII-7439XP501F;.ALPHA.-HYDROXYTRIMETHOPRIM;A876423;RACEMIC .ALPHA.-(2,4-DIAMINO-5-PYRIMIDYL)-3,4,5-TRIMETHOXYBENZYL ALCOHOL;G63608;DA-57474;ARD173319;Trimethoprim Impurity C (Ca-Hydroxy-TMP)
SMILES: COC1=CC(C(C2=CN=C(N)N=C2N)O)=CC(OC)=C1OC
Formula: C14H18N4O4
M.Wt: 306.31712
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12136_DC28080_29606-06-2
COA
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Cat. No. Product name Field of application
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DC72144 TH-Z145 TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).
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DC70368 DU011 DU011 is a noncanonical anti-infective agent and small-molecule inhibitor of capsule biogenesis, targets MprA (Kd=30 nM), a MarR family transcriptional repressor of multidrug efflux pumps, inhibits capsule expression in E. coli. DU011 does not alter Escherichia coli antibiotic resistance and has significantly enhanced inhibition of capsule expression, compared with other proposed MprA ligands, such as salicylate and 2,4-dinitrophenol (DNP).
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DC44112 2',3'-Dideoxy-5-iodocytidine 2',3'-Dideoxy-5-iodocytidine is used for gene sequencing can be used as an antibiotic. 2',3'-Dideoxy-5-iodocytidine is particular effective against Mycobacterium.
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