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Saccharin 1-methylimidazole (SMI)

  Cat. No.:  DC9903   Featured
Chemical Structure
482333-74-4
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More than 5000 active chemicals with high quality for research!
Field of application
SMI is considered a general-purpose activator for DNA and RNA synthesis.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 482333-74-4
Chemical Name: Saccharin 1-methylimidazole
SMILES: C1=CC=CC2S(=O)(=O)N=C([O-])C1=2.C1[NH+](C)C=CN=1
Formula: C11H11N3O3S
M.Wt: 265.287
Purity: >98%
Description: Saccharin 1-methylimidazole is an activator for DNA/RNA Synthesis.
Target: Target: DNA/RNA Synthesis[1]
In Vitro: Exposure to certain concentrations of the entirely different promoters phenobarbital and the calcium and sodium salts of saccharin (22, 23, 25, 29, 38) stimulates calcium-deprived T51B cells to initiate DNA synthesis as rapidly and as effectively, or nearly as effectively, as raising the extracellular calcium concentration to 1.25 mM[1].
References: [1]. Boynton AL, et al. Stimulation of DNA synthesis in calcium-deprived T51B liver cells by the tumor promoters phenobarbital, saccharin, and 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1980 Dec;40(12):4541-5.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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