Sanguinarine

  Cat. No.:  DCX-025   Featured
Chemical Structure
2447-54-3
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More than 5000 active chemicals with high quality for research!
Field of application
Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB. At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Sanguinarine chloride) usually boasts enhanced water solubility and stability.
Cas No.: 2447-54-3
Chemical Name: Sanguinarine
Synonyms: sanguinarine;1,3)-Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium,;[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-;SANGUINARINE (RG);Sanguinarium;Dimethylenedioxy benzphenanthridine;EINECS 219-503-3;Pseudochelerythrine;Sanguinarin;Sanguinarine Chloride;sanguninarine;sanquinarine;[ "Pseudochelerythrine" ];sangvinarin;Veadent;Sanguiritrin;C20H14NO4;Benzophenanthridine alkaloid;AV9VK043SS;DSSTox_RID_80748;DSSTox_CID_25204;DSSTox_GSID_45204;Sangrovit;y-Chelerythrine;SR-;SCHEMBL123241;IDI1_000495;DivK1c_000495;sanguinarium-chloride;KBio2_000739;13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium;13-methyl-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium;KBioSS_000739;KBioGR_002542;Prestwick1_000987;SPBio_002954;AB00053789_04;NCGC00160289-02;INVGWHRKADIJHF-UHFFFAOYSA-N;SR-01000075650-7;NCGC00015959-03;CCG-205184;Spectrum5_000635;EX-A5014;BRN 3915507;Tox21_110268;GTPL11563;2447-54-3;(1,3)BENZODIOXOLO(5,6-C)-1,3-DIOXOLO(4,5-I)PHENANTHRIDINIUM, 13-METHYL-;HY-N0052;NCGC00015959-02;Q-100313;Spectrum4_001838;BPBio1_001159;[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-;NCGC00015959-05;s9032;Pseudochelerythrine;Sanguinarin;NCGC00015959-16;HMS1571E15;pseudo-chelerythrine;SCHEMBL17131945;Spectrum_000259;SR-01000075650;NCGC00015959-01;E80766;CHEBI:17183;NCGC00015959-09;Q347392;NCGC00015959-04;MLS002154085;SDCCGMLS-0066612.P001;SANGUINARINE [WHO-DD];24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.0^{2,10.0^{4,8.0^{14,22.0^{17,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene;BSPBio_002675;13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium nitrate;NINDS_000495;HMS2098E15;CS-3818;Tox21_110268_1;compound 1 [PMID: 28621943];C06162;NCGC00160289-01;FT-0634289;AB00053789;AKOS025311557;KBio2_005875;SMR001233394;AC-34836;SBI-0051077.P003;13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium(1+), 9CI;BSPBio_001053;CHEMBL417799;CAS-2447-54-3;BRD-K66898851-001-03-7;DTXCID8025204;(1,3)-Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13-methyl-;BCP13614;24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium;Spectrum2_000724;13-methyl(1,3)benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium;24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14,16,21,23-nonaen-24-ium;KBio2_003307;UNII-AV9VK043SS;Prestwick2_000987;SANGUINARINE;x-Chelerythrine;13-Methyl[1,3]benzodioxolo[5,6-C][1,3]dioxolo[4,5-I]phenanthridin-13-Ium;24-methyl-5,7,18,20-tetraoxa-24-azoniahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(24),2,4(8),9,11,13,15,17(21),22-nonaene;13-methyl-2H,10H-(1,3)dioxolo(4,5-i)(1,3)dioxolo(4',5':4,5)benzo(1,2-c)phenanthridinium;Prestwick0_00...
SMILES: O1C([H])([H])OC2C([H])=C([H])C3C(C1=2)=C([H])[N+](C([H])([H])[H])=C1C2=C([H])C4=C(C([H])=C2C([H])=C([H])C1=3)OC([H])([H])O4
Formula: C20H14NO4
M.Wt: 332.3295
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: For the detailed information of Sanguinarine, the solubility of Sanguinarine in water, the solubility of Sanguinarine in DMSO, the solubility of Sanguinarine in PBS buffer, the animal experiment(test) (test) of Sanguinarine, the cell expriment (test) of Sanguinarine, the in vivo, in vitro and clinical trial test of Sanguinarine, the EC50, IC50,and Affinity of Sanguinarine,, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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