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Spadin TFA

  Cat. No.:  DC41833  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
Spadin TFA, a natural peptide derived from a propeptide released in blood, is able to block the TREK-1 (KCNK2 or K2P2.1) channel activity. Spadin TFA binds specifically to TREK-1 with an affinity of 10 nM. Spadin TFA is an efficient antidepressant in mice.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.:
Chemical Name: Spadin TFA
Synonyms: YAPLPRWSGPIGVSWGLR
Formula: C92H143F3N26O24
M.Wt: 2126.36
Sotrage: Protect from lightPowder-80°C2 years -20°C1 year*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
MSDS
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MSDS_24846_DC41833
COA
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Cat. No. Product name Field of application
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DC46366 ICA-105665 ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the blood-brain barrier and has antiseizure effects.
DC46296 Gliclazide (D4) Gliclazide D4 (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic.
DC45784 UCL 1684 dibromide UCL 1684 (dibromide) is a first nanomolar, non-peptidic small conductance calcium-activated potassium (SK) channel blocker. UCL 1684 (dibromide) is effective in preventing the development of atrial fibrillation due to potent atrial-selective inhibition of INa. UCL 1684 (dibromide) causes atrial-selective prolongation of ERP secondary to induction of postrepolarization refractoriness.
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