Topotecan hydrochloride|cas 119413-54-6|Supplied by DC Chem

Cas No.:	119413-54-6
Chemical Name:	(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride
Synonyms:	NSC 609699 NSC-609699 NSC609699; SKF S104864A. SKF 104864 A; SKF-104864-A; SKF104864A; TOPO. Hycamtamine; Hycamtin Hydrochloride; Nogitecan Hydrochloride; Topotecan; Nogitecan Hydrochloride; US brand name: Hycamtin.
SMILES:	O[C@@]1(CC)C(C=C2C(N=C3C=CC(O)=C(CN(C)C)C3=C4)=C4CN52)=C(COC1=O)C5=O.Cl
Formula:	C₂₃H₂₄ClN₃O₅
M.Wt:	457.91
Purity:	>98%, Standard References Grade
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:

For the detailed information about the solubility of Topotecan hydrochloride in water, the solubility of Topotecan hydrochloride in DMSO, the solubility of Topotecan hydrochloride in PBS buffer, the animal experiment（test） of Topotecan hydrochloride,the in vivo,in vitro and clinical trial test of Topotecan hydrochloride,the cell experiment（test） of Topotecan hydrochloride,the IC50, EC50 and Affinity of Topotecan hydrochloride, please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DCH-057	Trigonelline	>98%,Standard References
DCW-004	Citric acid	Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice.
DCB-029	Anemoside B4	Pulchinenoside B4 is a triterpenoid glycoside that inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities. Pulchinenoside B4 also prevents increases in plasma blood urea nitrogen (BUN) and creatinine levels -- markers of kidney injury.
DCG-043	Triolein	Triolein is a symmetric triacylglycerol that reduces upregulation of MMP-1 and has strong antioxidant and anti-inflammatory activities.
DCG-004	Glycyrrhizic acid	>98%,Standard References
DCF-003	Lycopene	>98%,Standard References
DCT-004	Crustecdysone	Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system. Crustecdysone is an active metabolite of Ecdysone (HY-N0179).
DCN-014	Tauroursodeoxycholic acid	Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
DCY-155	Eupalinolide B	>98%,Standard References
DCY-048	Topotecan hydrochloride	Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities.