ZK-200775|MPQX，ZK200775，ZK-200775|Purchase|DC CHEM

Cas No.:	161605-73-8
Synonyms:	MPQX，ZK200775，ZK-200775
SMILES:	O=C(N1CP(O)(O)=O)C(NC(C1=C2)=CC(C(F)(F)F)=C2N3CCOCC3)=O
Formula:	C₁₄H₁₅N₃O₆F₃P
M.Wt:	409.25
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ZK 200775 is a competitive GluR (AMPA)/kainate antagonist. In rat cortical membranes, it displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites but low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). It inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4.. For the detailed information of ZK-200775, the solubility of ZK-200775 in water, the solubility of ZK-200775 in DMSO, the solubility of ZK-200775 in PBS buffer, the animal experiment (test) of ZK-200775, the cell expriment (test) of ZK-200775, the in vivo, in vitro and clinical trial test of ZK-200775, the EC50, IC50,and affinity,of ZK-200775, Please contact DC Chemicals.

MSDS

COA

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2018-0101

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