ZM 323881 HCl|cas 193001-14-8|DC Chemicals

Cas No.:	193001-14-8
SMILES:	C1C=CC(COC2C=CC3C(NC4C=C(O)C(C)=CC=4F)=NC=NC=3C=2)=CC=1
Formula:	C₂₂H₁₈FN₃O₂^.HCl
M.Wt:	411.86
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

ZM 323881 hydrochloride is a potent and selective inhibitor of human Flk-1 (vascular endothelial growth factor receptor 2, VEGFR-2/KDR) activity. ZM 323881 hydrochloride inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). Selectively inhibits Flk-1 (VEGFR-2) (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases. ZM 323881 hydrochloride is an inhibitor of EGFR, Flg and PDGFR-β.

MSDS

COA

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2018-0101

Cat. No.	Product name	Field of application
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