Z-LEHD-FMK

  Cat. No.:  DC7569  
Chemical Structure
210345-04-3
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More than 5000 active chemicals with high quality for research!
Field of application
Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, therefore, are useful tools for studying Caspase activity.
Cas No.: 210345-04-3
Chemical Name: methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate
Synonyms: Z-LE(OMe)HD(OMe)-FMK, Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK, Z-Leu-Glu(OMe)-His-Asp(OMe)-Fluoromethylketone
SMILES: CC(CC(NC(OCC1=CC=CC=C1)=O)C(NC(C(NC(C(NC(C(CF)=O)CC(OC)=O)=O)CC2=CN=CN2)=O)CCC(OC)=O)=O)C
Formula: C32H43FN6O10
M.Wt: 690.72
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Cell permeable fluoromethyl ketone (FMK)-derivatized peptides act as effective irreversible Caspase inhibitors with no cytotoxic effects and, there Fore, are useful tools For studying Caspase activity.For the detailed information of Z-LEHD-FMK, the solubility of Z-LEHD-FMK in water, the solubility of Z-LEHD-FMK in DMSO, the solubility of Z-LEHD-FMK in PBS buffer, the animal experiment (test) of Z-LEHD-FMK, the cell expriment (test) of Z-LEHD-FMK, the in vivo, in vitro and clinical trial test of Z-LEHD-FMK, the EC50, IC50,and Affinity of Z-LEHD-FMK, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47247 Tyrosylleucine TFA Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243 Dehydroglyasperin C Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
DC47227 (−)-Myrtenal (−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
DC47224 GPX4-IN-3 GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179 Tyrosylleucine Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178 Mead acid Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140 Yadanzioside K Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105 Complanatoside B Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.
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