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CGS-21680

  Cat. No.:  DC42919   Featured
Chemical Structure
124182-57-6
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More than 5000 active chemicals with high quality for research!
Field of application
A potent and selective Adenosine receptor A2A agonist
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 124182-57-6
Chemical Name: CGS-21680 hydrochloride
Synonyms: CGS-21680 hydrochloride;3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydro-furan-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid hydrochloride;CGS21680;CGS-21680 hydrochloride hydrate;CGS 21680 hydrochloride,4-[2-[[6-Amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoicacidhydrochloride;CGS21680HCl;CGS-21680 hydrate hydrochloride;CGS-21680 HYDROCHLORIDE ADENOSINE AGONIS T;Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride;2-P-(2-CARBOXYETHYL)PHENETHYLAMINO-5'-N-ETHYLCARBOXAMIDOADENOSINE HYDROCHLORIDE;2-p-(2-Carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride hydrate;CGS-21680;CGS 21680;CGS-21680/CGS21680;CGS-21680 hydrochloride hydrate;3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid hydrochloride;MFCD00078573;MFCD11045878;Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, hydrochloride (1:1);CS-0425;CGS21680 HCL;AC-32733;124431-80-7;DTXSID2040999;Benzenepropanoic acid, 4-(2-((6-amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl)amino)ethyl)-, monohydrochloride;124182-57-6;REGID_for_CID_10256643;3-{4-[2-({6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid hydrochloride;CGS 21680 (Hydrochloride hydrate);MLS001056776;s2153;AKOS024456361;2-p-(2-Carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride;3-(4-(2-(6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-ylamino)ethyl)phenyl)propanoic acid hydrochloride;CGS21680hydrochloride;BCP9000512;CGS-21680 Hydrochloride hydrate; CGS21680 Hydrochloride hydrate;EX-A2473;CGS 21680 hydrochloride;MLS002153401;3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid;hydrochloride;CHEMBL537419;CGS 21680 HCl;HY-13201A;MLS006011122;4-[2-[[6-Amino-9-(N-ethyl-?-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride;Hydrochloride salt of (2-(p-2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine;CCG-269942;CGS 21680 (Hydrochloride);AS-75112;J-005077;Cgs 21680A;3-{4-[2-({6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid hydrochloride;2-p-(2-Carboxyethyl)phenethylamino-5'-N-ethylcarboxamidoadenosine hydrochloride hydrate;SMR000058796;CGS-21680 HYDROCHLORIDE;CGS 21680 hydrochloride?
SMILES: Cl.OC(CCC1C=CC(CCNC2=NC(N)=C3C(N(C4OC(C(NCC)=O)C(O)C4O)C=N3)=N2)=CC=1)=O
Formula: C23H29N7O6.HCl
M.Wt: 535.9806
Purity: >98%
Sotrage: 0°C (short term), -20°C (long term), desiccated
MSDS
TITLE DOWNLOAD
MSDS_26547_DC42919_124182-57-6
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC33635 DODAP DODAP, also known as 1,2-Dioleoyl-3-dimethylammonium-propane, is a cationic lipid. It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery.
DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC74583 ZK53 ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP). It exhibits an EC50 of 1.37 μM for α-casein hydrolysis by HsClpP. ZK53 treatment allosterically activates HsClpP to uncontrollably degrade the essential mitochondrial proteins and is inactive toward bacterial ClpP proteins.
DC74576 Fluorofurimazine Fluorofurimazine is a novel furimazine analogue, with increased aqueous solubility enabling higher signal emission than furimazine for bioluminescence imaging. Fluorofurimazine enables higher substrate loading and improved optical imaging sensitivity in in-vivo.
DC74557 PREX-in1 PREX-in1 is a specific small-molecule inhibitor of P-Rex1 and P-Rex2 Rac-GEF activity with IC50 of 4.5 uM (P-Rex1 DHPH Rac-GEF activity) in liposome-based GEF assay, inhibits P-Rex1 and P-Rex2 through their catalytic DH domain.
DC74555 GYS32661 GYS32661 (GYS 32661) is a potent Rac inhibitor capable of inhibiting both Rac1 and Rac1b, inhibited activated Rac1 with IC50 of 1.18 uM in in vitro pull-down assays.
DC74539 L557-0155 L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.
DC74528 K284 K284 is a selective small molecule inhibitor of chitinase 3 like1 (CHI3L1) with strong binding affinity (Kd=-9.7 kcal·mol-1), inhibits lung metastasis by blocking IL-13Rα2-mediated JNK-AP-1 signals.
DC74247 AG-946 AG-946 (AG946) is a potent, allosteric activator of wild-type and mutant RBC-specific form of pyruvate kinase (PKR) with AC50 of 5 nM for human wild-type PK, 4.3 nM and 6.9 nM for mutated K410E and R510Q PK proteins, resepctively.
DC74241 Rebecsinib Rebecsinib (17S-FD-895) is a selective small-molecule inhibitor of splicing-mediated ADAR1 activation, prevents leukemia stem cell generation.
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