DSPE-NHS |CAS 1383932-86-2|DC Chemicals

Cas No.:	1383932-86-2
Chemical Name:	DSPE-NHS
SMILES:	CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCC(ON1C(CCC1=O)=O)=O)=O)(O)=O)=O
Formula:	C₄₉H₈₉N₂O₁₃P
M.Wt:	945.21
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as drug nanocarrier.

Cat. No.	Product name	Field of application
DC68163	DSPE-PEG-DSS6	DSS6-PEG-DSPE,DSPE-PEG-DSS6 is a composite molecule composed of phospholipids(DSPE),polyethylene glycol(PEG),and bone targeting peptide DSS6,mainly used for bone targeted drug delivery and bone tissue repair. Its core structure achieves precise targeting and efficient delivery through the synergistic effect of three parts.The DSS6 peptide consists of six Asp-Ser-Ser amino acid repeat sequences and can specifically recognize hydroxyapatite(HAp)in bone tissue.
DC68155	DMG-PEG2000-Biotin	DMG-PEG2000-Biotin is a synthetic amphiphilic molecule composed of dimyristoyl glycerol (DMG), polyethylene glycol (PEG2000), and biotin functionalities. It is commonly employed in biomedical research for surface modification of lipid-based delivery platforms, such as lipid nanoparticles (LNPs) and liposomes. The PEG moiety enhances colloidal stability, prolongs circulation time, and reduces rapid clearance in vivo. The biotin termination facilitates conjugation to streptavidin-tagged biomolecules, exploiting the highly specific biotin-streptavidin interaction. Thus, DMG-PEG2000-Biotin is valuable for drug-delivery optimization, targeted therapeutic approaches, and in vitro diagnostic assay development.
DC68154	Thiol-PEG2000-DMG	Thiol-PEG2000-DMG is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
DC68153	DMG-PEG2000-OH	DMG-PEG2000-OH is a PEG derivative that can be used to construct drug delivery vehicles.
DC68152	DMG-PEG2000-SH	DMG-PEG2000-SH is a PEG derivative that can be used to construct drug delivery vehicles.
DC67619	DMG-PEG-TCO (MW2000)	DMG-PEG2000-TCO offer the ability to easily conjugate to specific biomolecules via metal free click chemistry to tetrazines. By changing the PEG length, one can change the micelle size, immunological safety, and change the drug release rate.
DC67603	DMG-PEG-Mal, MW 2,000	DMG-PEG-Mal, MW 2,000 is a lipid PEG consisting of DMG and maleimide for reacting with thiols between pH 6.5 to 7.5
DC67571	DMG-PEG-Mannose	DMG-PEG-Mannose is a specialized functionalized lipid used primarily for the targeted delivery of lipid nanoparticles (LNPs) and liposomes to cells expressing mannose receptors, such as macrophages and dendritic cells. It combines a 1,2-dimyristoyl-sn-glycerol (DMG) lipid anchor with a polyethylene glycol (PEG) spacer and a terminal mannose sugar moiety.
DC67097	DSPE-PEG(2000)-amine (sodium salt)	DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095). It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents. DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4 It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.
DC67096	DMG-PEG-NHS (MW2000)	DMG-PEG2000-NHS is a PEG derivative that can be used in various biomedical applications, such as the construction of drug delivery systems (siRNA delivery liposomes, lipid nanoparticle, etc.). The active ester (NHS) can react with an amino group (-NH2) to form a stable amide bond, which can be used as a linker in a bioconjugation strategy to modify amino-linked peptide proteins as well as other small molecules.