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DX3-235

  Cat. No.:  DC49011  
Chemical Structure
2749555-39-1
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More than 5000 active chemicals with high quality for research!
Field of application
DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-235 shows nanomolar inhibition of complex I function and ATP production in a galactose-containing medium resulting in significant cytotoxicity.
Cas No.: 2749555-39-1
Chemical Name: DX3-235
Formula: C26H39NO5S
M.Wt: 581.75
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_32910_DC49011_2749555-39-1
COA
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Cat. No. Product name Field of application
DC49761 BAY-179 BAY-179 is a potent, selective, and species cross-reactive complex I inhibitor (IC50=79 µM).
DC49760 THP104c THP104c is a mitochondrial fission inhibitor.
DC42141 D-Histidine D-Histidine is an enantiomer of L-histidine. L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
DC40140 Mitochondrial fusion promoter M1 Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury.
DC28781 NL-1 NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 µM and 56.26 µM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway.
DC72224 Clidanac Clidanac is a potent anti-inflammatory agent. Clidanac can uncouple the oxidative phosphorylation and can be used for the research of rheumatoid arthritis.
DC71815 MFI8 MFI8 is a small molecule inhibitor of mitochondrial fusion.
DC49763 Complex III-IN-2 Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor. Complex III-IN-2 shows antifungal activity with an EC50 of 29.98 mg/L and 29.31 mg/L against sclerotinia sclerotiorum and R. solani, respectively.
DC49762 Complex III-IN-1 Complex III-IN-1 (Compd 4c-2) is a complex III inhibitor. Complex III-IN-1 shows antifungal activity with an EC50 of 18.53 mg/L against sclerotinia sclerotiorum.
DC49759 DX3-213B DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer.
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